G-PROTEIN ## reliure PEPTIDE 1 pc x 1 mg

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

Reversible: no

Primary TargetG-protein βγ

Product does not compete with ATP.

Cell permeable: yes

General description

A cell-permeable, N-myristoylated G-Protein Binding Peptide (mSIRK) that contains a single point mutation (Leu⁹ to Ala). In contrast to mSIRK (Cat. No. 371818), the mutant peptide is unable to enhance ERK1/2 phosphorylation. Useful as a negative control for mSIRK.

A cell-permeable, single point mutated (Leu⁹ to Ala), N-myristoylated G-protein βγ Binding Peptide (mSIRK). Does not enhance ERK1/2 phosphorylation and serves as a negative control for studies involving mSIRK (Cat. No. 371818).

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Goubaeva, F., et al. 2003. J. Biol. Chem.278, 19634.Scott, J.K., et al. 2001. EMBO J.20, 767.

Packaging

Packaged under inert gas

1 mg in Glass bottle

Physical form

Supplied as a trifluoroacetate salt.

Reconstitution

Following reconstitution aliquot and freeze(-20°C). Stock solutions are stable for up to 4 months at -20°C.

Sequence

Myr-N-Ser-Ile-Arg-Lys-Ala-Leu-Asn-Ile-Ala-Gly-Tyr-Pro-Asp-Tyr-Asp-OH

Warning

Toxicity: Standard Handling (A)