RO5256390

Code: SML1893-5MG D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

RO5256390 is an agonist of Trace amine-associated receptor 1 (TAAR1), a GPCR primarily found in the brain, expressed in areas where the major monoamin...


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$137.31 5MG
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Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

RO5256390 is an agonist of Trace amine-associated receptor 1 (TAAR1), a GPCR primarily found in the brain, expressed in areas where the major monoamine amine transmitters (DA and NE) are also present. RO5256390 is a selective TAAR1 agonist shown to be a negative regulator of dopamine transmission. It has antipsychotic activity in models of schizophrenia, reduces cocaine′s reinforcng effects, and blocks binge-eating disorder.

assay≥98% (HPLC)
colorwhite to beige
formpowder
optical activity[α]/D 14 to 19°, c = 1 in methanol
Quality Level100
SMILES stringCC[C@@H](C[C@H]1COC(N)=N1)C2=CC=CC=C2
solubilityDMSO: 10 mg/mL, clear
storage temp.2-8°C
Cas Number1043495-96-0
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :



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