Non disponible en dehors du Royaume-Uni et de l'Irlande
Biochem/physiol Actions
AS8351 is an iron chelator that has been found to inhibit of histone demethylase KDM5B (JARID1B), a histone H3K4 demethylase involved in regulation of cell proliferation and stem cell self-renewal and differentiation. AS8351 is thought to inhibit KDM5B by competing with a-ketoglutarate for chelating iron that KDM5B requires as a co-factor.
Packaging
5, 25 mg in glass bottle
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :