FEBUXOSTAT

Code: SML1285-1G D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

Febuxostat is a potent non-purine xanithine oxidase inhibitor. Febuxostat is used in urate lowering therapies (ULTs) for the treatment of gout.

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$273.28 1G

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

Febuxostat is a potent non-purine xanithine oxidase inhibitor. Febuxostat is used in urate lowering therapies (ULTs) for the treatment of gout.

Caution

Freely soluble in N,N-dimethyl formamide, Soluble in dimethyl sulfoxide, sparingly soluble in ethanol or trichloromethane, slightly soluble in methanol, practically insoluble in water

General description

Febuxostat is a potent, non-purine compound, which inhibits the expression of cytokines/chemokines. It has also been reported to inhibit LPS-induced TNF-α, VCAM-1, MMP9 and MCP-1 expression.

assay98.5-102.0% (HPLC)
formpowder
InChI keyBQSJTQLCZDPROO-UHFFFAOYSA-N
InChI1S/C16H16N2O3S/c1-9(2)8-21-13-5-4-11(6-12(13)7-17)15-18-10(3)14(22-15)16(19)20/h4-6,9H,8H2,1-3H3,(H,19,20)
Quality Level200
SMILES stringCC(C)COC1=C(C#N)C=C(C2=NC(C)=C(C(O)=O)S2)C=C1
storage temp.2-8°C
Cas Number144060-53-7
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :



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