MLS000389544, >=98% (HPLC)

Code: SML0290-5MG D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

MLS000389544 is a selective and potent methylsulfonylnitrobenzoate thyroid hormone receptor β (TRβ) antagonist that blocks the association o...


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Votre prix
$156.19 5MG
Abandonné

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

MLS000389544 is a selective and potent methylsulfonylnitrobenzoate thyroid hormone receptor β (TRβ) antagonist that blocks the association of TRβ with steroid receptor coactivator 2 (SRC2). It effectively block TR-mediated gene transcription. MLS000389544 is selective for TR over other NR family members. It appears to act by irreversible mechanisms and target cysteine residues in the coactivator binding pocket.

Features and Benefits

This compound is featured on the Nuclear Receptors (Non-Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorwhite to beige
formpowder
InChI keyBTXTVUJWNPMQBT-UHFFFAOYSA-N
InChI1S/C20H24N2O7S/c1-30(27,28)17-3-2-15(7-16(17)22(25)26)19(24)29-11-18(23)21-20-8-12-4-13(9-20)6-14(5-12)10-20/h2-3,7,12-14H,4-6,8-11H2,1H3,(H,21,23)
Quality Level100
SMILES stringCS(=O)(=O)c1ccc(cc1[N+]([O-])=O)C(=O)OCC(=O)NC23CC4CC(CC(C4)C2)C3
solubilityH2O: ≥5 mg/mL (warmed)
storage temp.−20°C
Cas Number573965-48-7
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :



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