C2 dihydrocérium (D18:0/2 : 0)

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

C2 Dihydroceramide (d18:0/2:0) has been used as a lipid standard in the analysis of sphingolipids by tandem mass spectrometry. It is also suitable for inducing stress in embryos to study stress-induced apoptosis in larval embryos of Japanese flounder.

Biochem/physiol Actions

Dihydroceramide is synthesized by the N-acylation of dihydrosphingosine. It functions as an inactive precursor for ceramide in de novo sphingolipid synthesis. (Dihydro)-ceramide desaturase catalyzes the conversion of dihydroceramide to ceramide by the addition of C4−5 trans-double bond in the sphingoid backbone. Dihydroceramide has an ability to induce autophagy.

General description

Dihydroceramide belongs to the ceramide family. It contains sphinganine, which is devoid of the 4,5-trans-double bond in the sphingoid base backbone.

Packaging

5 mL Amber Glass Screw Cap Vial (860625P-5mg)