18:0 LYSO PA

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

18:0 Lyso PA is suitable for use:to determine the extraction recovery of LPA at neutral pH and acidic pH by chromatographic method to use as internal standard to study the role of intestinally derived lysophosphatidic acid in dyslipidemia and atherosclerosisto investigate its effects on clathrin?dependent endocytosis

Biochem/physiol Actions

Lysophosphatidic acid (1- or 2-acyl-lysophosphatidic acid/LPA) modulates cell motility, proliferation, invasion, survival and production of growth factors via G protein-coupled receptor (GPCR).

General description

Lysophosphatidic acid (1- or 2-acyl-lysophosphatidic acid/LPA), a bioactive phospholipid is seen at a low level in plasma (~100nM). It is usually formed during the synthesis of phospholipid of cell membranes. It is produced by various cells like, activated platelets, epithelial cells, leukocytes, neuronal cells and tumor cells. 18:0 Lyso PA has stearic acid atsn-1 and a hydroxyl group atsn-2 position.

Packaging

5 mL Amber Glass Screw Cap Vial (857128P-25mg)