Non disponible en dehors du Royaume-Uni et de l'Irlande
General description
A potent competitive inhibitor of cytidine deaminase. Used in combination with cytosine arabinoside (Ara-C) to assess the anti-leukemic activity and anti-tumor activity of Ara-C in in vitro studies.
Potent competitive inhibitor of cytidine deaminase. Also available as a 100 mM solution in H2O(Cat. No. 584223).
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Other Notes
Yusa, K., et al. 1995. Biochem. Biophys. Res. Commun. 206, 486.Bouffard, D.Y., et al. 1993. Biochem Pharmacol.45, 1857.Laliberte, J., et al. 1992. Cancer Chemotherap. Pharmacol.30, 7.Riva, C., et al. 1992. Chemotherapy38, 358. Yusa, K., et al. 1992. J. Biol. Chem. 267, 16848.Hanze, A.R. 1967. J. Am. Chem. Soc.89, 6720.
Packaging
Packaged under inert gas
10 mg in Plastic ampoule
Reconstitution
Following reconstitution, aliquot, purge with inert gas, and freeze (-20°C). Aqueous stock solutions (at neutral or basic pH) are stable for up to 3 months at -20°C.
Warning
Toxicity: Standard Handling (A)
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :