trans-4-Hydroxy - l-proline,BioXtra ,> = 99,0%( NT)

Name: trans-4-Hydroxy - l-proline,BioXtra ,> = 99,0%( NT)
Brand: SIGMA-ALDRICH
SKU: 56250-5G
Price: 50.89 USD

Code: 56250-5G D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

Trans-4-Hydroxy-L-proline is used as a starting material in the synthesis of (-)-secrinine; the synthesis of prolinol-based nucleotide analogues with ...

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Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

Trans-4-Hydroxy-L-proline is used as a starting material in the synthesis of (-)-secrinine; the synthesis of prolinol-based nucleotide analogues with N-phosphonomethyl moiety attached to the nitrogen atom of prolinol ring and in asymmetric synthesis of the ABC-ring system of the antitumor antibiotic MPC1001.

Trans-4-Hydroxy-L-proline is used in the organic synthesis of depsilairdin analogues, noncompetitive peptidomimetic inhibitors of multidrug resistance P-glycoprotein and 3-guaninyl-5-hydroxymethyl-2-pyrrolidinone (4) or 3-adeninyl-5-hydroxymethyl-2-pyrrolidinone (5) nucleoside analogues.

Other Notes

Natural constituent of animal structural proteins such as collagen and elastin.

Enzymes and intermediates of hydroxyproline degradation

anion traces	sulfate (SO₄^2-): ≤100 mg/kg, chloride (Cl^-): ≤100 mg/kg
application(s)	peptide synthesis
assay	≥99.0% (NT)
cation traces	Na: ≤50 mg/kg, K: ≤50 mg/kg, Cr: ≤5 mg/kg, Mn: ≤5 mg/kg, Mg: ≤5 mg/kg, Ca: ≤10 mg/kg, Pb: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, NH₄⁺: ≤100 mg/kg, Zn: ≤5 mg/kg, Ni: ≤5 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg
color	colorless to white
form	solid
ign. residue	≤0.1% (as SO₄)
impurities	≤0.3% foreign amino acids
InChI key	PMMYEEVYMWASQN-DMTCNVIQSA-N
InChI	1S/C5H9NO3/c7-3-1-4(5(8)9)6-2-3/h3-4,6-7H,1-2H2,(H,8,9)/t3-,4+/m1/s1
loss	≤0.1% loss on drying, 110 °C
mp	273 °C (dec.) (lit.)
optical activity	[α]20/D −76.0±1.5°, c = 5% in H₂O
product line	BioXtra
Quality Level	100
SMILES string	O[C@H]1CN[C@@H](C1)C(O)=O

Safety Data Sheet for 56250-5G
Certificat d'analyse Sigma

Cas Number

51-35-4

Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :

trans-4-Hydroxy - l-proline,BioXtra ,> = 99,0%( NT)

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