Non disponible en dehors du Royaume-Uni et de l'Irlande
General description
A cell-permeable, Au(I)-phosphine complex that acts as selective inhibitor of lymphoid tyrosine phosphatase (LYP) (IC50= 1.5 µM) and has a ~10-fold selectivity for LYP over PTP-PEST, HePTP, and CD45 in both JTAg cells and primary mouse thymocytes.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Other Notes
Karver, M.R., et al. 2009. J. Med. Chem.52, 6912.
Reconstitution
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Warning
Toxicity: Standard Handling (A)
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :