Non disponible en dehors du Royaume-Uni et de l'Irlande
Biochem/physiol Actions
Reversible: no
Primary Targetα-subunit of G-proteins
Product does not compete with ATP.
Cell permeable: yes
General description
A cell-permeable, amphiphilic, mastoparan analog with five-fold greater potency than Mastoparan Cat. No. 444898. An activator of α-subunit of G-proteins. Evokes rapid upregulation of FAK tyrosine phosphorylation via activation of G-proteins.
Mastoparan analog with five-fold greater potency than mastoparan. An activator of the α-subunit of G -proteins. Evokes a rapid upregulation of FAK tyrosine phosphorylation via activation of G-proteins.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Other Notes
Mironov, S.L., and Richter, D.W. 2000. Brain Res.853, 60.Park, H.S., et al. 2000. Biochim. Biophys. Acta1484, 151.Zhang, C., et al. 1996. FEBS Lett. 386, 185.Leyte, A., et al. 1992. EMBO J.11 4795.Higashijima, T., et al. 1990. J. Biol. Chem.265, 14176.
Packaging
1 mg in Plastic ampoule
Yes
Physical form
Supplied as a trifluoroacetate salt.
Reconstitution
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Sequence
H-Ile-Asn-Leu-Lys-Ala-Leu-Ala-Ala-Leu-Ala-Lys-Ala-Leu-Leu-NH₂
Warning
Toxicity: Standard Handling (A)
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :