Non disponible en dehors du Royaume-Uni et de l'Irlande
Biochem/physiol Actions
Cell permeable: no
Reversible: no
Product does not compete with ATP.
Primary TargetInhibits the activation of Gq by M1-muscarinic cholinergic receptors
General description
A peptide that selectively inhibits the activation of Gq by M1-muscarinic cholinergic receptors. Also inhibits activation by cholecystokinin receptor in pancreatic acini at 10 µM. Blocks angiotensin II-stimulated sis-inducing factor and STAT3 tyrosine phosphorylation.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Other Notes
Hunt, R.A., et al. 1999. Hypertension34, 603.Tsunoda Y., et al. 1995. Biochem. Biophys. Res. Commun. 211, 648.Mukai, H., et al. 1992. J. Biol. Chem.267, 16237.
Packaging
1 mg in Plastic ampoule
Sequence
H-Arg-Pro-Lys-Pro-Gln-Gln-D-Trp-Phe-D-Trp-D-Trp-Met-NH₂
Warning
Toxicity: Standard Handling (A)
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :