Non disponible en dehors du Royaume-Uni et de l'Irlande
Biochem/physiol Actions
binds trypsin in the picomolar range
Product does not compete with ATP.
Primary Targetserine proteases
Target IC50: 1 pM against serine proteases
General description
A potent, broad range inhibitor of serine proteases.
A potent, broad range inhibitor of serine proteases. Exhibits picomolar binding constant for the inhibition of chymotrypsin, elastase, Factor Xa, Factor XIIa, kallikrein, and trypsin. Also acts as an effective inhibitor of collagenase.
A potent, broad range inhibitor or serine proteases. Exhibits picomolar binding constant for the inhibition of chymotrypsin, elastase, Factor Xa, Factor XIIa, kallikrein, and trypsin. Also an effective inhibitor of collagenase and granzyme B.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Other Notes
McGrath, M.E., et al. 1995. Protein Sci. 4, 141.Seong, I.S., et al. 1994. J. Biol. Chem. 269, 21915.McGrath, M.E., et al. 1991. J. Biol. Chem. 266, 6620.
Packaging
100 µg in Plastic ampoule
Please refer to vial label for lot-specific concentration.
Physical form
In 1.0 mM HCl.
Reconstitution
Following initial thaw, aliquot and freeze (-70°C).
Warning
Toxicity: Standard Handling (A)
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :