Non disponible en dehors du Royaume-Uni et de l'Irlande
Biochem/physiol Actions
Cell permeable: no
Reversible: no
Product does not compete with ATP.
Primary TargetNitric oxide scavenging action
General description
Reacts with nitric oxide at pH 7.4, resulting in the generation of NO2-/NO3- with a rate constant of 1 x 104 M-1sec-1. Prevents SIN-1 induced endothelial cell death. Reported to have potent therapeutic value in endotoxin shock through its nitric oxide scavenging action.
Reacts with nitric oxide at pH 7.4, resulting in the generation of NO2-/NO3- with a rate constant of 1 x 104 M-1sec-1. Prevents SIN-1 induced endothelial cell death. Has potent therapeutic value in endotoxin shock through its nitric oxide scavenging action.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Other Notes
Ishii, M., et al., 1999. J. Cardiovasc. Pharmacol. 33, 295.Amano, F., and Nova, J. 1995. FEBS Lett.368, 425.Hogg, N., et al. 1995. Free Radical Res.22, 47.Az-ma, T., et al. 1994. Life Sci.54, 185.Yoshida, M., et al. 1994. Biochem. Biophys. Res. Commun.202, 923.Akaike, T., et al. 1993. Biochemistry32, 827.Yoshida, K., et al. 1993. Infect. Immun.61, 3552.
Packaging
Packaged under inert gas
10 mg in Plastic ampoule
Reconstitution
Following reconstitution, refrigerate (4°C). Aqueous stock solutions are stable for up to 1 week at 4°C.
Warning
Toxicity: Standard Handling (A)
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :