Methyl chloroformate, 99%

Not available outside of the UK & Ireland.

Application

Methyl chloroformate (MCF) is generally used for the derivatization of functional groups such as carboxylic acids, amines, and phenols.MCF can also be used:To activate 3-acylpyridines for nucleophilic addition with alkynyltin reagents to form 2,3-disubstituted 1,2-dihydropyridines.Chloroesterification of terminal alkynes to form β-chloro-α,β-unsaturated esters.As an electrophilic reagent to mediate the reaction of pyridine with lithium dialkyl- or diarylcuprates to form 4-substituted 1,4-dihydropyridine derivatives.To convert nitronates into methoxycarbonyl nitronates.

Packaging

5 g in glass bottle

100, 500 g in Sure/Seal™