(4S)-4-Hydroxy-L-isoleucine, from fenugreek seed, >=98.0% (TLC)

Code: 50118-50mg D2-231

Not available outside of the UK & Ireland.

Biochem/physiol Actions

(4S)-4-Hydroxy-L-isoleucine (HIL) is a non-proteinogenic A amino acid produced by the activity of bacterial isoleucine dioxygenase(s). (2S,3R,4S)-HIL ...


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$620.60 50MG
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Not available outside of the UK & Ireland.

Biochem/physiol Actions

(4S)-4-Hydroxy-L-isoleucine (HIL) is a non-proteinogenic A amino acid produced by the activity of bacterial isoleucine dioxygenase(s). (2S,3R,4S)-HIL is being studied to understand its insulinotropic (anti-diabetic) and anti-obesity effects.

4-Hydroxyisoleucine (HIL) from fenugreek (Trigonella foenum-graecum) seeds is a potential insulinotropic (anti-diabetic) and anti-obesity amino acid. HIL stimulates glucose-dependent insulin secretion from pancreatic cells. HIL activates insulin receptor substrate-associated phosphoinositide 3 (PI3) kinase activity. HIL reduces plasma levels of triglycerides, free fatty acids and cholesterol.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

assay≥98.0% (TLC)
biological sourcefenugreek seeds
colorwhite to almost white
formpowder or flakes
InChI keyOSCCDBFHNMXNME-YUPRTTJUSA-N
InChI1S/C6H13NO3/c1-3(4(2)8)5(7)6(9)10/h3-5,8H,7H2,1-2H3,(H,9,10)/t3-,4-,5-/m0/s1
optical activity[α]/D +32.5±2.0°, c = 1 in H2O
Quality Level100
SMILES stringC[C@H](O)[C@H](C)[C@H](N)C(O)=O
storage temp.2-8°C
Cas Number781658-23-9
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