Nitisinone, >=95% (HPLC)

Code: sml0269-10mg D2-231

Not available outside of the UK & Ireland.

Application

Nitisinone has been used:to induce liver injuryto treat Ixodes scapularis tick cells to inhibit the activity of hydroxyphenylpyruvate dioxygenasein suppl...


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Your Price
$145.39 10MG
REQUEST

Not available outside of the UK & Ireland.

Application

Nitisinone has been used:to induce liver injuryto treat Ixodes scapularis tick cells to inhibit the activity of hydroxyphenylpyruvate dioxygenasein supplemented water to block the accumulation of toxic metabolites in human hepatocyte engrafted miceto study its effect on bacterial pyomelanin production

Biochem/physiol Actions

Nitisinone is a competitive inhibitor that reversibly inhibits 4-Hydroxyphenylpyruvate oxidase (dioxygenase). Nitisinone is used in the treatment of hereditary tyrosinemia type 1, where it blocks the degradation of tyrosine into harmful substances.

Packaging

10, 50 mg in glass bottle

assay≥95% (HPLC)
colorwhite to brown
formpowder
Gene Informationhuman ... HPD(3242)
InChI keyOUBCNLGXQFSTLU-UHFFFAOYSA-N
InChI1S/C14H10F3NO5/c15-14(16,17)7-4-5-8(9(6-7)18(22)23)13(21)12-10(19)2-1-3-11(12)20/h4-6,12H,1-3H2
Quality Level100
SMILES string[O-][N+](=O)c1cc(ccc1C(=O)C2C(=O)CCCC2=O)C(F)(F)F
solubilityDMSO: ≥5 mg/mL
storage temp.−20°C
Cas Number104206-65-7
This product has met the following criteria to qualify for the following awards:



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