AEG 3482, >=98% (HPLC)

Code: sml0264-5mg D2-231

Not available outside of the UK & Ireland.

Biochem/physiol Actions

AEG3284 is a compound that binds to heat shock protein 90 (HSP90), leading to heat shock factor 1 (HSF1) dependent expression of HSP70, an endogenous ...


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$152.12 5MG
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Not available outside of the UK & Ireland.

Biochem/physiol Actions

AEG3284 is a compound that binds to heat shock protein 90 (HSP90), leading to heat shock factor 1 (HSF1) dependent expression of HSP70, an endogenous inhibitor of c-Jun N-terminal kinase (JNK) activity. Treatment of PC12 cells with AEF3284 blocks JNK dependent apoptosis.

AEG 3482 is an imidazothiadiazole sulfonamide of 281 D with an anti-apoptotic property.

Features and Benefits

This compound is featured on the MAPKs page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorfaintly yellow to dark yellow
formpowder
InChI keyMQUYTXDAVCOCMX-UHFFFAOYSA-N
InChI1S/C10H8N4O2S2/c11-18(15,16)10-13-14-6-8(12-9(14)17-10)7-4-2-1-3-5-7/h1-6H,(H2,11,15,16)
Quality Level100
SMILES stringNS(=O)(=O)c1nn2cc(nc2s1)-c3ccccc3
solubilityDMSO: ≥15 mg/mL
storage temp.2-8°C
Cas Number63735-71-7
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