ARL-17477 dihydrochloride hydrate, >=98% (HPLC)

Code: sml0178-5mg D2-231

Not available outside of the UK & Ireland.

Application

ARL-17477 dihydrochloride hydrate may be used in cell signaling studies.

Biochem/physiol Actions

ARL-17477 is an nNOS specific inhibi...


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Your Price
$178.16 5MG
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Not available outside of the UK & Ireland.

Application

ARL-17477 dihydrochloride hydrate may be used in cell signaling studies.

Biochem/physiol Actions

ARL-17477 is an nNOS specific inhibitor. The IC50 against rat nNOS is 35 nM and it has 100-fold selectivity over endothelial and inducible isoforms. ARL-17477 penetrates the brain, and reduces infarct size and reduces cerebral blood flow in several different rodent models of ischemic brain injury.

Features and Benefits

This compound was developed by AstraZeneca. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorwhite to beige
formpowder
InChI keyQOPATWWWZNTSQF-UHFFFAOYSA-N
InChI1S/C20H20ClN3S.2ClH.H2O/c21-17-4-1-3-16(13-17)14-23-11-10-15-6-8-18(9-7-15)24-20(22)19-5-2-12-25-19;;;/h1-9,12-13,23H,10-11,14H2,(H2,22,24);2*1H;1H2
originatorAstraZeneca
Quality Level100
SMILES stringO.Cl.Cl.Clc1cccc(CNCCc2ccc(NC(=N)c3cccs3)cc2)c1
solubilityH2O: ≥5 mg/mL
storage conditiondesiccated
storage temp.2-8°C
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