S15535, >=98% (HPLC), solid

Not available outside of the UK & Ireland.

Application

S15535 may be used in histamine 5-HT_1A-medaited cell signaling studies.

S15535 has been used as a serotonin 1A receptor (5-HT1A) agonist in zebrafish.

Biochem/physiol Actions

S15535, a benzodioxane, is a selective but partial agonist of histamine serotonin 1A (5-HT_1A) receptor. It activates presynaptic 5-HT_1A receptors and suppresses the release of hippocampal 5-HT. It acts as an anxiolytic agent and modulates the cholinergic and cognitive function in rodents.

Potent, orally active, partial 5-HT_1A receptor agonist

Packaging

25 mg in glass bottle