5beta-Pregnan-3alpha-ol-20-one,

Code: p8129-25mg D2-231

Not available outside of the UK & Ireland.

Biochem/physiol Actions

5β-Pregnan-3α-ol-20-one or pregnanolone is a neurosteroid that acts as a positive allosteric modulator (PAMs) of γ-aminobutyric acid A receptors (GABA...


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$236.93 25MG
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Not available outside of the UK & Ireland.

Biochem/physiol Actions

5β-Pregnan-3α-ol-20-one or pregnanolone is a neurosteroid that acts as a positive allosteric modulator (PAMs) of γ-aminobutyric acid A receptors (GABAARs). It mediates anti-convulsive, anxiolytic and sedative effects. Pregnanolone inhibits γ-aminobutyric acid C receptor (GABAC) receptor-based response and favors GABAAreceptor-mediated currents.

Packaging

25 mg in glass insert

assay≥98% (TLC)
biological sourcesynthetic (organic)
formpowder
Gene Informationrat ... Gabra2(29706)
InChI keyAURFZBICLPNKBZ-UHFFFAOYSA-N
InChI1S/C21H34O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h14-19,23H,4-12H2,1-3H3
Quality Level100
shipped inambient
SMILES string[H]C12CCC3C4CCC(C(C)=O)C4(C)CCC3C1(C)CC[C@H](O)C2
solubilitychloroform: 50 mg/mL, clear, colorless
storage temp.room temp
Cas Number128-20-1
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