5alpha-Pregnan-3alpha-ol-11,20-dione, powder, >=98% (TLC)

Code: p5052-10mg D2-231

Not available outside of the UK & Ireland.

Biochem/physiol Actions

Synthetic steroid compound alphaxalone (AFX) - 5A-Pregnan-3A-ol-11,20-dione- is a neurosteroid that directly activates and potentiates GABAA

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$257.12 10MG
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Not available outside of the UK & Ireland.

Biochem/physiol Actions

Synthetic steroid compound alphaxalone (AFX) - 5A-Pregnan-3A-ol-11,20-dione- is a neurosteroid that directly activates and potentiates GABAA receptor-activated membrane current (IGABA). It acts as a positive allosteric modulator of the GABAA receptor; anesthetic. The alpha subunit subtype of GABAA determines the efficacy, but not the potency, of AFX neuroactive steroid to potentiate IGABA.

assay≥98% (TLC)
colorwhite
drug controlUSDEA Schedule IV
formpowder
Gene Informationhuman ... GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562), GABRG2(2566)
InChI keyDUHUCHOQIDJXAT-OLVMNOGESA-N
InChI1S/C21H32O3/c1-12(22)16-6-7-17-15-5-4-13-10-14(23)8-9-20(13,2)19(15)18(24)11-21(16,17)3/h13-17,19,23H,4-11H2,1-3H3/t13-,14+,15-,16+,17-,19+,20-,21+/m0/s1
Quality Level200
SMILES string[H][C@@]12CC[C@@]3([H])[C@]4([H])CC[C@H](C(C)=O)[C@@]4(C)CC(=O)[C@]3([H])[C@@]1(C)CC[C@@H](O)C2
solubilitychloroform: ≥5 mg/mL, clear, colorless
Cas Number23930-19-0
Hazard Class6.1
Un Number2811
Pack GroupIII
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