Methyl-3,4-dephostatin, , >98% (HPLC), powder

Code: m9440-1mg D2-231

Not available outside of the UK & Ireland.

Application

Methyl-3,4-dephostatin has been used as: an inhibitor for methyltransferases a kinase-related inhibitor for human transglutaminasea cysteine binding compound for ...


 Read more

Your Price
$232.89 1MG
REQUEST

Not available outside of the UK & Ireland.

Application

Methyl-3,4-dephostatin has been used as: an inhibitor for methyltransferases a kinase-related inhibitor for human transglutaminasea cysteine binding compound for screening its effect on C-terminal domain (CTD) of human immunodeficiency virus (HIV-1) capsid protein

Biochem/physiol Actions

Stable analog of dephostatin; selective protein tyrosine phosphatase 1B and SHPTP-1 inhibitor; does not inhibit CD45-associated phosphatases.

Methyl-3,4-dephostatin is a tyrphostin-related compound isolated from Streptomyces MJ742-NF5 strain. It favors nerve growth factor-based neurite formation in pheochromocytoma PC12 cells. Being a stable analog of the nitrosoaniline dephostatin, it can mimic phosphotyrosine substrate for Tyrosyl-DNA phosphodiesterase I (TdpI).

assay>98% (HPLC)
colorred-brown
formpowder
Gene Informationhuman ... PTPN1(5770)
InChI keyXAKAQCMEMMZUEO-UHFFFAOYSA-N
InChI1S/C7H8N2O3/c1-9(8-12)5-2-3-6(10)7(11)4-5/h2-4,10-11H,1H3
Quality Level100
SMILES stringCN(N=O)c1ccc(O)c(O)c1
solubilityDMSO: soluble 18 mg/mL, H2O: insoluble
storage temp.2-8°C
This product has met the following criteria to qualify for the following awards:



PROCEED TO CHECKOUT

HAVE AN ACCOUNT? LOGIN
GUEST CHECKOUT

Proceed as a guest. You will have the option to register to access exclusive pricing and stock availability features after checkout.