Not available outside of the UK & Ireland.
Application
MPP dihydrochloride hydrate has been used as an estrogen receptor α antagonist:in human breast cancer MCF-7 cellsto pre-treat endometrial ex vivo organ cultures (EVOCs)to treat pituitary glands to monitor luteinizing hormone secretion
Biochem/physiol Actions
Methyl-piperidino-pyrazole hydrate (MPP) is an agonist for estrogen receptor α and lacks any ligand functionality with estrogen receptor (ER)β. It promotes silibinin induced apoptosis in human breast cancer MCF-7 cells.
MPP dihydrochloride is a specific estrogen receptor α antagonist.
General description
Methyl-piperidino-pyrazole hydrate (MPP) is prepared from a methyl-pyrazole-triol (MPT), a pyrazole triol.
Packaging
10, 25 mg in glass bottle
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