MPP dihydrochloride hydrate, >=97% (HPLC), white powder

Code: m7068-25mg D2-231

Not available outside of the UK & Ireland.

Application

MPP dihydrochloride hydrate has been used as an estrogen receptor α antagonist:in human breast cancer MCF-7 cellsto pre-treat endometrial ex vivo organ c...


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Your Price
$491.94 25MG
Discontinued

Not available outside of the UK & Ireland.

Application

MPP dihydrochloride hydrate has been used as an estrogen receptor α antagonist:in human breast cancer MCF-7 cellsto pre-treat endometrial ex vivo organ cultures (EVOCs)to treat pituitary glands to monitor luteinizing hormone secretion

Biochem/physiol Actions

Methyl-piperidino-pyrazole hydrate (MPP) is an agonist for estrogen receptor α and lacks any ligand functionality with estrogen receptor (ER)β. It promotes silibinin induced apoptosis in human breast cancer MCF-7 cells.

MPP dihydrochloride is a specific estrogen receptor α antagonist.

General description

Methyl-piperidino-pyrazole hydrate (MPP) is prepared from a methyl-pyrazole-triol (MPT), a pyrazole triol.

Packaging

10, 25 mg in glass bottle

assay≥97% (HPLC)
colorwhite
formpowder
InChI keyFWDNPWVVRVSJQH-UHFFFAOYSA-N
InChI1S/C29H31N3O3.2ClH/c1-21-28(22-5-11-25(33)12-6-22)30-32(24-9-13-26(34)14-10-24)29(21)23-7-15-27(16-8-23)35-20-19-31-17-3-2-4-18-31;;/h5-16,33-34H,2-4,17-20H2,1H3;2*1H
Quality Level100
SMILES stringCl.Cl.Cc1c(nn(-c2ccc(O)cc2)c1-c3ccc(OCCN4CCCCC4)cc3)-c5ccc(O)cc5
solubilityDMSO: soluble ≥20 mg/mL
Cas Number911295-24-4
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