Not available outside of the UK & Ireland.
Biochem/physiol Actions
Inhibits 5-lipoxygenase of guinea pig leukocytes with an IC50 of 10 µM. In extracts of rat basophilic leukemia cells preincubated with 5,6-dehydro AA, the Ki for the conversion of arachidonic acid to 5-HPETE is 15 µM.
General description
An analog of arachidonic acid in which the 5,6 double bond has been replaced with an acetylene group.
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