Monoclonal anti-sorcs3

Not available outside of the UK & Ireland.

General description

This gene encodes one family member of vacuolar protein sorting 10 (VPS10) domain-containing receptor proteins. The VPS10 domain name comes from the yeast carboxypeptidase Y sorting receptor Vps10 protein. Members of this gene family are large with many exons but the CDS lengths are usually less than 3700 nt. Very large introns typically separate the exons encoding the VPS10 domain; the remaining exons are separated by much smaller-sized introns. These genes are strongly expressed in the central nervous system. Two of the five family members (sortilin and sortilin-related receptor) are synthesized as preproproteins; it is not yet known if this encoded protein is also a preproprotein. (provided by RefSeq)

Immunogen

SORCS3 (NP_055793, 1147 a.a. ~ 1222 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.SequenceKRKIPWINIYAQVQHDKEQEMIGSVSQSENAPKITLSDFTEPEELLDKELDTRVIGGIATIANSESTKEIPNCTSV

Legal Information

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Physical form

Solution in phosphate buffered saline, pH 7.4