Monoclonal Anti-PMM2 antibody produced in mouse, clone 2E9, purified immunoglobulin, buffered aqueous solution

Not available outside of the UK & Ireland.

General description

The protein encoded by this gene catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate, which is a precursor to GDP-mannose necessary for the synthesis of dolichol-P-oligosaccharides. Mutations in this gene have been shown to cause defects in glycoprotein biosynthesis, which manifests as carbohydrate-deficient glycoprotein syndrome type I. (provided by RefSeq)

Immunogen

PMM2 (NP_000294, 47 a.a. ~ 111 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.SequenceSDFEKVQEQLGNDVVEKYDYVFPENGLVAYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIK

Legal Information

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Physical form

Solution in phosphate buffered saline, pH 7.4