Monoclonal anti-blm

Not available outside of the UK & Ireland.

Features and Benefits

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General description

The Bloom syndrome gene product is related to the RecQ subset of DExH box-containing DNA helicases and has both DNA-stimulated ATPase and ATP-dependent DNA helicase activities. Mutations causing Bloom syndrome delete or alter helicase motifs and may disable the 3′-5′ helicase activity. The normal protein may act to suppress inappropriate recombination. (provided by RefSeq)

Immunogen

BLM (NP_000048, 1196 a.a. ~ 1295 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.SequenceSSVKKQKALVAKVSQREEMVKKCLGELTEVCKSLGKVFGVHYFNIFNTVTLKKLAESLSSDPEVLLQIDGVTEDKLEKYGAEVISVLQKYSEWTSPAEDS

Legal Information

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Physical form

Solution in phosphate buffered saline, pH 7.4