Anticorps phospho-Cortactin (pTyr466) produit en lapin, environ 1 mg/mL, anticorps isolé affinité, solution aqueuse tamponnée

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Anti-phospho-Cortactin (pTyr421) antibody has been used in western blotting and immunoprecipitation.

Biochem/physiol Actions

Cortactin controls Arp2/3-mediated actin polymerization. This protein also modulates aggressive cancer cell traits like tumor growth, cancer cell invasion and motility, and serum and anchorage-independent growth.

Disclaimer

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Features and Benefits

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General description

Cortactin is an actin-related protein 2/3 (Arp2/3) complex–activating and filamentous (F)-actin–binding protein. This protein is coded by CTTN gene that maps to human chromosome 11q13.

Immunogen

The antiserum was produced against synthesized peptide derived from mouse Cortactin around the phosphorylation site of Tyr466.Immunogen Range: 441-490

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.