Anti-SRPK1 antibody produced in rabbit, approx. 1 mg/mL, affinity isolated antibody, buffered aqueous solution

Not available outside of the UK & Ireland.

Biochem/physiol Actions

Serine-arginine protein kinase 1 (SRPK1) modulates angiogenesis. Suppressing SRPK1 prevents the development and migration in renal carcinoma cells. In normoxic condition, SRPK1 can increase the migration and invasion of glioma cells.

Features and Benefits

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General description

Anti-SRPK1 Antibody detects endogenous levels of total SRPK1 protein.Serine-arginine protein kinase 1 (SRPK1) belongs to the SR kinase family. In mammals, SRPK1 is expressed in the central nervous system in a region- and neuron-specific manner. This gene is mapped to human chromosome 6p21.2-p21.3. SRPK1 is also expressed in several normal tissues like testis and pancreas.

Immunogen

The antiserum was produced against synthesized peptide derived from human SRPK1.Immunogen Range: 521-570

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.