ANTI-HUMAN IGG (GAMMA-CHAIN SPECIFIC) M

Not available outside of the UK & Ireland.

Application

Anti-Human IgG (γ-chain specific) antibody, Mouse monoclonal has been used in indirect ELISA.

Biochem/physiol Actions

Immunoglobulins (Igs) serve as key players in the humoral immune response.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Anti-Human IgG (γ-chain specific) antibody, Mouse monoclonal (mouse IgG1 isotype) is derived from the GG-5 hybridoma, produced by the fusion of mouse myeloma cells and splenocytes from mouse immunized with purified human IgG. Immunoglobulins (Igs) are produced by B lymphocytes and secreted into the plasma. Immunoglobulins can be divided into five main classes/isotypes which are IgA, IgD, IgE, IgG, and IgM. IgG class identity is determined by class-specific sequences in the Fc region of the heavy chain. IgG antibody class are the most abundant immunoglobulins isotype in blood, lymph fluid, cerebrospinal fluid and peritoneal fluid. IgGs include four subclasses (IgG1, IgG2, IgG3, and IgG4). The IgG subclasses differ in their physical and chemical properties. Their distribution pattern is found to be age dependent and every subclass has a specific biological function.

Immunogen

purified human IgG

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.