ANTI-CHD1 (C-TERMINAL) ANTIBODY PROD+

Not available outside of the UK & Ireland.

Application

Anti-CHD1 (C-terminal) antibody from rabbit has been used in immunoblotting and immunofluorescence.

Biochem/physiol Actions

Chromodomain-helicase-DNA-binding protein 1 (CHD1) modifies chromatin structure affecting the interaction of transcriptional apparatus to its chromosomal DNA template. CHD1 is required for maintaining open chromatin and pluripotency in embryonic stem cells (ESCs).

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Chromodomain-helicase-DNA-binding protein 1 (CHD1) is an ATP-dependent chromatin-remodeling factor. The CHD family of proteins contains two domains : chromo (chromatin organization modifier) and SNF2-related helicase/adenosine triphosphatase (ATPase).

Immunogen

synthetic peptide corresponding to the C-terminal region of human CHD1 , conjugated to KLH.

Physical form

a solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide