Anti-B7-H4 antibody produced in goat, affinity isolated antibody, buffered aqueous solution

Not available outside of the UK & Ireland.

Biochem/physiol Actions

V-set domain containing T cell activation inhibitor 1 (VTCN1) has a role in T-cell mediated immune responses. It suppresses T-cell action by inhibiting cytokine secretion and the proliferation of cells. VTCN1 has a role in pancreatic cancer and it also promotes tumor immune invasion.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

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General description

V-set domain containing T cell activation inhibitor 1 (VTCN1), also known as B7-H4, is a co-stimulating molecule. It is part of the B7 superfamily and the gene encoding it is localized on human chromosome 1p13.1.

Immunogen

Peptide with sequence C-SKGKGNANLEYK from the internal region of the protein sequence according to NP_078902.2.

Physical form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.