ANTI-VNN2 (N-TERM)

Not available outside of the UK & Ireland.

General description

VNN2 is a member of the Vanin family of proteins which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. The encoded protein is a GPI-anchored cell surface molecule that plays a role in transendothelial migration of neutrophils.

Immunogen

VNN2 (NP_004656, )This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human VNN2.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.