Anti-Gfl-1 (N-term) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution

Not available outside of the UK & Ireland.

General description

Gfl-1 encodes a C. elegans ortholog of human Glioma-amplified sequence-41 (GAS41), found in increased copy number in low-grade glioma. Loss of GLF-1, which is predicted to associate with chromatin, results in potent suppression of the RNA interference (RNAi) mechanism. GLF-1 is also similar to the transcription factors (yeast and human) AF-9 and human ENL, and thus may represent a novel class of transcription factors.

Immunogen

GFL (NP_502172, )This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of C. Elegans Gfl-1.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.