Anti-SCDGFB (center) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution

Not available outside of the UK & Ireland.

General description

Potent mitogen for cells of mesenchymal origin. Binding of this growth factor to its affinity receptor elicits a variety of cellular responses. It is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound. Activated by proteolytic cleavage and this active form acts as a specific ligand for beta platelet-derived growth factor receptor. Induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis.

Immunogen

SCDGFB (Q9EQT1, )This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human SCDGFB.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.