Anti-GCAP3 (N-term) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution

Not available outside of the UK & Ireland.

General description

GCAP3 stimulates guanylyl cyclase 1 (GC1) and GC2 when free calcium ion concentration is low and inhibits guanylyl cyclases when free calcium ion concentration is elevated This Ca(2+) sensitive regulation of guanylyl cyclase (GC) is a key event in recovery of the dark state of rod photoreceptors following light exposure. GCAP3 contains 4 EF-hand calcium-binding domains and is expressed in the retina.

Immunogen

GCAP3 (31-66)This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human GCAP3.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.