Anti-Thymosin beta-4

Not available outside of the UK & Ireland.

Analysis Note

ControlRecombinant Thymosin beta-4

Application

Western Blot (Snap i.d.™) Analysis: 1 µg/mL from a previous lot detected Thymosin beta-4 on 10 µg of recombinant Thymosin beta-4.

Immunocytochemistry Analysis: 1:500 dilution from a previous lot detected Thymosin beta-4 in NIH/3T3, HeLa, and A431 cells.

Anti-Thymosin beta-4 Antibody is an antibody against Thymosin beta-4 for use in WB & IC.

General description

Thymosin beta-4 is the most prevalent of the cytoplasmic G-actin binding proteins belonging to the highly conserved thymosin beta family. Known to bind actin monomers, Thymosin beta-4 sequesters G-actin in a manner that prevents actin polymerization. Thymosin beta-4 plays several important roles including induction of tissue remodeling, wound healing in both cell and tissue injuries, and cell differentiation via mechanisms that have yet to be fully elucidated. It is involved in the regulation of the cytoskeleton, and thereby influences an array of cellular processes. Within the brain, Thymosin beta-4 is associated with the neurite extension and migration of neurons. Expression has been observed in various hemopoietic and lymphoid malignant cell lines.

Immunogen

GST-tagged recombinant protein corresponding to the internal domain of human Thymosin beta-4.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Quality

Evaluated by Western Blot in recombinant Thymosin beta-4.

Western Blot Analysis: 1 µg/mL of the antibody detected Thymosin beta-4 on 10 µg of recombinant Thymosin beta-4.

Specificity

Th antibody recognizes the internal domain of Thymosin beta-4.

Target description

~ 33kDa observed