Anti-phospho - SYK(pTyr323) anticorps produit dans un anticorps isolé rabbit affinity

Code: sab4300282-100ug D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

Spleen tyrosine kinase (SYK) is a tumor suppressor gene that helps to prevent the development and metastasis of breast cancer cells. It participates i...


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$506.17 100UG

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

Spleen tyrosine kinase (SYK) is a tumor suppressor gene that helps to prevent the development and metastasis of breast cancer cells. It participates in B-cell receptor signaling. The protein helps to phosphorylate the α-tubulin subunits of microtubules. SYK aids in the coupling of receptors for antigen-antibody complexes. It also modulates cell proliferation and differentiation.

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General description

Spleen tyrosine kinase (SYK) is a member of the non-receptor tyrosine kinase family. It is usually expressed in epithelial breast tissues and hematopoietic cells. The gene encoding it is localized on human chromosome 9q22.

Immunogen

Peptide sequence around phosphorylation site of tyrosine 323 (N-P-Y(p)-E- P), according to the protein SYK.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

antibody formaffinity isolated antibody
antibody product typeprimary antibodies
biological sourcerabbit
clonepolyclonal
concentration1 mg/mL
conjugateunconjugated
formbuffered aqueous solution
Gene Informationhuman ... SYK(6850)
immunogen sequence(N-P-YP-E-P)
isotypeIgG
mol wt~72 kDa
NCBI accession no.NP_001128524.1
Quality Level100
shipped inwet ice
species reactivityhuman, rat, mouse
storage temp.−20°C
technique(s)western blot: 1:500-1:1000, immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100, indirect immunofluorescence: 1:100-1:200
UniProt accession no.P43405
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :



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