Anti-CHAK1 (C-term) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution

Not available outside of the UK & Ireland.

General description

TRPCs, mammalian homologs of the Drosophila transient receptor potential (trp) protein, are ion channels that are thought to mediate capacitative calcium entry into the cell. TRP-PLIK is a protein that is both an ion channel and a kinase. As a channel, it conducts calcium and monovalent cations to depolarize cells and increase intracellular calcium. As a kinase, it is capable of phosphorylating itself and other substrates. The kinase activity is necessary for channel function, as shown by its dependence on intracellular ATP and by the kinase mutants.[supplied by OMIM]

Immunogen

CHAK1 (Q9BXB2, 1825-1859)This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human CHAK1.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.