PACAP 27 AMIDE, OVINE 1PC X 0.5MG

Not available outside of the UK & Ireland.

Biochem/physiol Actions

Cell permeable: no

Reversible: no

EC50 = 4.7 nM increasing cAMP levels in a dose-dependent manner

Product does not compete with ATP.

Primary TargetIncreases cAMP levels

General description

Increases cAMP levels in a dose-dependent manner (EC₅₀ = 4.7 nM). Increases tyrosine hydroxylase expression in chromaffin cells.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Kobayashi, H., et al. 1994. Brain Res.647, 145.Tatsuno, I., et al. 1990. Biochem. Biophys. Res. Commun. 168, 1027.

Packaging

Yes

Physical form

Supplied as a trifluoroacetate salt.

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Sequence

H-His-Ser-Asp-Gly-Ile-Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-NH₂

Warning

Toxicity: Standard Handling (A)