RANIRESTAT

Code: sml1315-5mg D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

Ranirestat (AS-3201) is an aldose reductase (AR) inhibitor. Aldose reductase is a rate-limiting enzyme in the conversion of D-glucose to fructose via ...


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Votre prix
$255.78 5MG

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

Ranirestat (AS-3201) is an aldose reductase (AR) inhibitor. Aldose reductase is a rate-limiting enzyme in the conversion of D-glucose to fructose via D-sorbitol. Ranirestat has been implicated in diabetic complications (cataract formation, retinopathy, neuropathy, nephropathy). Ranirestat prevents sorbitol accumulation and is thus hoped to be effective in the remedy of diabetic neuropathy.

Packaging

5, 25 mg in glass bottle

assay≥97% (HPLC)
colorwhite to beige
formpowder
InChI keyQCVNMNYRNIMDKV-QGZVFWFLSA-N
InChI1S/C17H11BrFN3O4/c18-10-4-3-9(11(19)6-10)8-21-14(24)12-2-1-5-22(12)17(16(21)26)7-13(23)20-15(17)25/h1-6H,7-8H2,(H,20,23,25)/t17-/m1/s1
optical activity[α]/D -5 to -10°, c = 1.0 in methanol
Quality Level100
SMILES stringO=C(N1CC2=C(F)C=C(Br)C=C2)C3=CC=CN3[C@@]4(CC(NC4=O)=O)C1=O
solubilityDMSO: 20 mg/mL, clear
storage temp.−20°C
Cas Number147254-64-6
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :



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