ACIDE ÉTHACRYNIQUE

Code: sml1083-10mg D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

Ethacrynic acid increases the cytotoxicity of chlorambucil in rat and human tumor cell lines.

Ethacrynic acid is non sulfonamide loop diuretic t...


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$57.75 10MG
DEMANDER

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

Ethacrynic acid increases the cytotoxicity of chlorambucil in rat and human tumor cell lines.

Ethacrynic acid is non sulfonamide loop diuretic that is used to treat high blood pressure and the swelling caused by diseases like congestive heart failure. Ethacrynic acid blocks sodium-potassium-chloride cotransport. Also, Ethacrynic acid potently inhibits glutathione S-transferase family members. Studies show that ethacrynic acid potently inhibits Tgase-2 (transglutaminase-2) dependent metastasis of cancer cells including lung and pancreatic cancers.

Packaging

10 mg in glass bottle

assay≥97% (HPLC)
colorwhite to beige
formpowder
Gene Informationhuman ... SLC12A1(6557)
InChI keyAVOLMBLBETYQHX-UHFFFAOYSA-N
InChI1S/C13H12Cl2O4/c1-3-7(2)13(18)8-4-5-9(12(15)11(8)14)19-6-10(16)17/h4-5H,2-3,6H2,1H3,(H,16,17)
Quality Level100
SMILES stringClC1=C(Cl)C(C(C(CC)=C)=O)=CC=C1OCC(O)=O
solubilityDMSO: 20 mg/mL, clear
storage temp.2-8°C
Cas Number58-54-8
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :



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