NS5806, >=98% (HPLC)

Code: N2540-5MG D2-231

Not available outside of the UK & Ireland.

Biochem/physiol Actions

NS5806 increases peak current amplitude of the potassium channel Kv4.3 (EC50 = 5.3 uM). NS5806 also slows Kv4.3 and Kv4.2 current dacay in channel com...


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$222.12 5MG
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Not available outside of the UK & Ireland.

Biochem/physiol Actions

NS5806 increases peak current amplitude of the potassium channel Kv4.3 (EC50 = 5.3 uM). NS5806 also slows Kv4.3 and Kv4.2 current dacay in channel complexes containing KChIP2. In ventricular cardiomycytes, NS5806 increases transient outward current and reproduces the electrocardiographic profile of Brugada syndrome.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorwhite to faint yellow
formpowder
InChI keyUZWJWROOLOOCPQ-UHFFFAOYSA-N
InChI1S/C16H8Br2F6N6O/c17-8-4-10(13-27-29-30-28-13)12(11(18)5-8)26-14(31)25-9-2-6(15(19,20)21)1-7(3-9)16(22,23)24/h1-5H,(H2,25,26,31)(H,27,28,29,30)
Quality Level100
SMILES stringFC(F)(F)c1cc(NC(=O)Nc2c(Br)cc(Br)cc2-c3nnn[nH]3)cc(c1)C(F)(F)F
solubilityDMSO: >30 mg/mL
storage temp.2-8°C
Cas Number426834-69-7
Hazard Class6.1
Un Number2811
Pack Group3
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