W-5; Hydrochloride

Not available outside of the UK & Ireland.

Biochem/physiol Actions

Reversible: yes

Product does not compete with ATP.

Target IC₅₀: 230 µM and 240 µM against myosin light chain kinase and Ca2+-calmodulin-dependent phosphodiesterase, respectively.

Cell permeable: yes

General description

A cell-permeable and reversible calmodulin antagonist that inhibits myosin light chain kinase (IC₅₀ = 230 µM) and Ca²⁺-calmodulin-dependent phosphodiesterase (IC₅₀ = 240 µM).

A cell-permeable and reversible calmodulin antagonist that inhibits Ca²⁺-calmodulin-dependent phosphodiesterase (IC₅₀ = 240 µM) and myosin light chain kinase (IC₅₀ = 230 µM).

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Packaging

1 mg in Plastic ampoule

Warning

Toxicity: Standard Handling (A)