Non disponible en dehors du Royaume-Uni et de l'Irlande
Biochem/physiol Actions
Primary Targetu Opioid receptpr
General description
A highly potent octapeptide that acts as a selective and brain penetrating bioavailable µ opioid receptor antagonist (IC50 = 3.5 nM). Used in studies of reward systems and additions.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Other Notes
Perry, C., et al., 2013. Behav. Neurosci.127, 535.Burkett, J. et al. 2011. Neuropsychopharm.36, 2200.Steinmiller, L., et al., 2008. Psychopharmacol. (Berl).195, 497.Sterious, S., et al., 2003. J. Pharmacol. Exp. Ther.304, 301.Abbruscato, T., et al. 1997. J. Pharmacol.280, 402.
Packaging
1 mg in Glass bottle
Reconstitution
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Sequence
D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH2 (2-7 disulfide bond)
Warning
Toxicity: Standard Handling (A)
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :