Non disponible en dehors du Royaume-Uni et de l'Irlande
Biochem/physiol Actions
Primary Target5-HT Uptake Transporter
General description
A very potent uptake inhibitor highly selective for 5-HT transporter (Ki = 0.065 nM and 0.05 nM for human and rat 5-HT transporters, respectively). A popular antidepressant drug of the SSRI type. Used to treat major depression, obsessive-compulsive disorder, panic disorder, social anxiety, posttraumatic stress disorder, generalized anxiety disorder and vasomotor symptoms.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Other Notes
Brittain, G., et al. 2012. Profiles of drug substances, excipients, and related methodology.38, 407.Bourin, M., et al. 2001. CNS Drug Rev.7, 25.Thomas, R., et al. 1997. Psychopharmacology (Berl).93, 193.
Packaging
10 mg in Glass bottle
Reconstitution
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Warning
Toxicity: Standard Handling (A)
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