5-Fluoro-L-tryptophan, >=98.0% (HPLC)

Code: 47568-25MG-F D2-231

Not available outside of the UK & Ireland.

Application

Exogenous 5-fluoro-Trp is incorporated into proteins in normal protein synthesis. Since 19F is a useful reporter group, this provides a method for stud...


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$132.74 25MG
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Not available outside of the UK & Ireland.

Application

Exogenous 5-fluoro-Trp is incorporated into proteins in normal protein synthesis. Since 19F is a useful reporter group, this provides a method for studying enzyme mechanisms by NMR.

Biochem/physiol Actions

5-Fluoro-Trp is nonspecifically cytotoxic. It is believed this is due to malfunctioning enzymes that have had replacements of Trp residues by 5-fluoro-Trp. However, at least one case is known where 5-fluoro-Trp substitution leads to significantly greater catalytic activity.

Packaging

25 mg in poly bottle

assay≥98.0% (HPLC)
formpowder
InChI keyINPQIVHQSQUEAJ-VIFPVBQESA-N
InChI1S/C11H11FN2O2/c12-7-1-2-10-8(4-7)6(5-14-10)3-9(13)11(15)16/h1-2,4-5,9,14H,3,13H2,(H,15,16)/t9-/m0/s1
mp270-280 °C
optical purityenantiomeric ratio: ≥99.5:0.5 (HPLC)
SMILES stringN[C@@H](Cc1c[nH]c2ccc(F)cc12)C(O)=O
storage temp.2-8°C
Cas Number16626-02-1
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