Non disponible en dehors du Royaume-Uni et de l'Irlande
Biochem/physiol Actions
Cell permeable: no
Reversible: yes
Primary Targetgranzyme B
Product does not compete with ATP.
General description
A reversible inhibitor of Granzyme B that also inhibits caspase-8. Granzyme B is a protease involved in the induction of rapid target cell death by cytotoxic lymphocytes.
A reversible inhibitor of granzyme B and caspase-8.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Other Notes
Harris, J.L., et al. 1998. J. Biol. Chem. 273, 27364.Thornberry, N.A., et al. 1997. J. Biol. Chem.272, 17907.
Packaging
1 mg in Plastic ampoule
Reconstitution
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Sequence
Ac-Ile-Glu-Pro-Asp-CHO
Warning
Toxicity: Standard Handling (A)
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :