Anti-Nanos1

Non disponible en dehors du Royaume-Uni et de l'Irlande

Analysis Note

ControlRat brain tissue lysate

Application

Detect Nanos homolog 1 using this rabbit polyclonal antibody, Anti-NANOS1 Antibody validated for use in western blotting & IHC.

Research CategoryCell Structure

Research Sub CategoryAdhesion (CAMs)

Immunohistochemistry Analysis: 2.5 µg/mL from a representative lot detected NANOS1 in human brain tissue.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Nanos homolog 1 (NANOS1, NOS-1) contains one nanos-type zinc finger and belongs to the nanos family. It is an RNA-binding protein that is predominantly expressed in testis during germline development. NANOS 1 is highly expressed in lung carcinomas that can be detected in invasive tumor cells. NANOS1 up-regulates the production of MMP14 to promote tumor cell invasion.

Immunogen

KLH-conjugated linear peptide corresponding to the intermediate domain of human NANOS1.

Epitope: Intermediate domain

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Quality

Evaluated by Western Blotting in rat brain tissue lysate.

Western Blotting Analysis: 2 µg/mL of this antibody detected NANOS1 in 15 µg of rat brain tissue lysate.

Specificity

This antibody recognizes the intermediate domain of NANOS1.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Target description

~42 kDa observed